AdvaGenix: Leaders in Next Generation Sequencing, Sanger Sequencing, Mixed Ligation Probe Assay (MLPA), and qPCR
AdvaGenix is the first all-encompassing preimplantation genetics laboratory that employs next generation sequencing for all testing.
AdvaGenix is especially attractive to IVF clinics desiring the use of Next Generation Sequencing as the testing strategy for their patients and their preimplantation embryos.
We also offer patients the ability to forgo embryo freezing and transfer the genetically normal embryos the day after embryo biopsy.

Traditional DNA sequencing, called Sanger sequencing, is a method that permits the sequence analysis of between approximately 30 base pairs to 800 base pairs from one DNA fragment as compared to a reference genome. It is a very accurate method for a specific DNA sequence. Its applications include determining a specific DNA mutation or variant but it cannot also simultaneously determine chromosome abnormalities.
The benefits of next generation sequencing
The high demand for affordable sequencing has driven the development of high throughput sequencing, which is called Next Generation sequencing. In contrast to traditional Sanger sequencing, Next Generation Sequencing concurrently sequences thousands or millions of DNA fragments ranging in sizes from approximately 150 base pairs to over 600 base pairs.
The key difference versus Sanger sequencing is the simultaneous sequencing of millions of fragments of DNA, their comparison to a reference genome, the ability to determine mitochondrion copy number and to simultaneously determine chromosome abnormalities, ALL at the same time.

AdvaGenix: Equipment
Biomek i7 Automated Workstation
- Biomek i7 Automated Workstation has been designed to optimize dependability and walk-away time in high-throughput labs
- Biomek i7 Automated Workstation has been designed to optimize dependability and walk-away time in high-throughput labs
NovaSeq 6000
- Applications requiring large amounts of data, such as human whole-genome sequencing (WGS), ultradeep exome sequencing
- Flow Cell Type SP G
- Gene Expression profiling
- Whole transcriptome analysis
- Exome
- Whole Genome
- Methylation (Epigenetics)
- Liquid biopsy
- Applications requiring large amounts of data, such as human whole-genome sequencing (WGS), ultradeep exome sequencing
- Flow Cell Type SP G
- Gene Expression profiling
- Whole transcriptome analysis
- Exome
- Whole Genome
- Methylation (Epigenetics)
- Liquid biopsy
QIAGEN Clinical Insight (QCI™) Interpret brings the World’s Knowledge of Disease Alterations to the Clinical Labs
Examples
Clinical Insight
Rare and Hereditary diseases
- Rare diseases
- Undiagnosed diseases
- Hereditary disorders
- Learning disabilities
- Hearing loss
- Neurological disorders
- Whole exome
- Whole genome
- Universal carrier screening
- Preimplantation genetic screening
- Prenatal screening
Clinical Insight
Hereditary Cancer
- Hereditary breast and ovarian cancer (HBOC)
- Lynch syndrome
- Li-Fraumeni syndrome
- Familial adenomatous polyposis (FAP)
- Cowden syndrome
- Multiple endocrine neoplasia
- etc
Clinical Insight
Cardiovascular
- Cardiopathies
- Arrhythmia
- Hereditary Arrhythmogenic
- Right Ventricular Cardiomyopathy
- (ARVC)
- Dilated Cardiomyopathy (DCM)
- Hypertrophic Cardiomyopathy (HCM)
- Left Ventricular Non-Compaction
- Cardiomyopathy (LVNC)
- Catecholaminergic Polymorphic
- Ventricular Tachycardia (CPVT)
- Long QT Syndrome (LQTS)
- and Brugada Syndrome
- Short QT syndrome (SQTS)
Clinical Insight
Rare and Hereditary diseases
- Rare diseases
- Undiagnosed diseases
- Hereditary disorders
- Learning disabilities
- Hearing loss
- Neurological disorders
- Whole exome
- Whole genome
- Universal carrier screening
- Preimplantation genetic screening
- Prenatal screening
Clinical Insight
Hereditary Cancer
- Hereditary breast and ovarian cancer (HBOC)
- Lynch syndrome
- Li-Fraumeni syndrome
- Familial adenomatous polyposis (FAP)
- Cowden syndrome
- Multiple endocrine neoplasia
- etc
Clinical Insight
Cardiovascular
- Cardiopathies
- Arrhythmia
- Hereditary Arrhythmogenic
- Right Ventricular Cardiomyopathy
- (ARVC)
- Dilated Cardiomyopathy (DCM)
- Hypertrophic Cardiomyopathy (HCM)
- Left Ventricular Non-Compaction
- Cardiomyopathy (LVNC)
- Catecholaminergic Polymorphic
- Ventricular Tachycardia (CPVT)
- Long QT Syndrome (LQTS)
- and Brugada Syndrome
- Short QT syndrome (SQTS)
Industry’s Largest, Most Up-to-Date Knowledge Base
Knowledge Base Update Frequency
- Clinical trials: weekly
- FDA/EMA labels: weekly
- Primary literature: weekly
- Guidelines (e.g. NCCN, ESMO): quarterly
- Databases: quarterly