Genetic Test Panels at AdvaGenix
AdvaGenix is the first to offer next-generation sequencing, Sanger sequencing and qPCR for all genetic testing. This advanced technology is available for:
- Diagnostic gene testing.
- Reproductive health testing.
- Personalized medicine.
- Cancer testing.
- Whole genome and clinical exome sequencing.
- Pharmacogenomics.
Below are full explanations of each test and the number of genes they include.
Jump ahead:
Cancer | Diagnostic gene testing | Reproductive health | Pharmacogenomics & metabolism | Neurological disorders
Hereditary cancer gene panels
- Comprehensive 138 inherited genes panel for eight major organ systems.
- Oncogene sequencing multi-gene with BRCA1/2 (32 genes).
- (30 genes).
- Lynch cancer panel (54 genes).
- Colon cancer panels (11 genes).
- Colon plus cancer panel (29 genes).
- Breast/ovarian uterine full panel (22 genes).
- Breast plus cancer panel (12 genes).
- Ovarian cancer panel (21 genes).
- BRCA cancer panel (2 genes).
- Prostate cancer panel (19 genes).
- Comprehensive hereditary cancer gene panel (176 genes).
- Whole exome hereditary cancer gene panel across all organ systems (877 genes).
Organ system specific hereditary gene panels (breast and other female organs)
- Basic breast cancer panel (2 genes).
- Expended high risk breast cancer panel (9 genes).
- Genes associated with hereditary breast, ovarian, endometrial and fallopian tube cancers (35 genes).
Endocrine organ panel
- Panel of genes associated with hereditary paraganglioma-pheochromocytoma syndrome, hereditary hyperparathyroidism, thyroid and parathyroid cancers, and other endocrine cancers (28 genes).
Gastrointestinal organ panels
- Panel of genes associated with actionable risk of developing colorectal and other associated cancers, such as ovarian, endometrial and thyroid (26 genes).
- Panel of genes associated with hereditary gastric cancer and other cancer types (19 genes).
- Panel of genes associated with hereditary pancreatic cancer, exocrine tumors and pancreatic neuroendocrine cancers, and chronic pancreatitis (28 genes).
Hematological tumor panel
- Panel of genes associated with a predisposition to myelodysplastic syndrome, leukemia and lymphoma.
Skin
- Panel of genes associated with a lifetime risk of developing melanomas as well as other cancers (12 genes).
Nervous system
- Panel of genes associated with hereditary paraganglioma-pheochromocytoma syndrome (14 genes).
- Panel of genes associated with hereditary brain tumor panel (27 genes).
- Panel of genes associated with hereditary cancers of the central and peripheral nervous system brain (40 genes).
Pediatric cancers
- Comprehensive hereditary pediatric cancer panel including solid tumors, soft tissue tumors and hematologic cancers (56 genes).
- Panel of 32 genes associated with hereditary pediatric cancers of the central and peripheral nervous system (32 genes).
- Panel of 16 genes associated with a predisposition to childhood hematologic cancers (16 genes).
- Panel of 48 genes associated with predisposition to pediatric solid tumors.
Genitourinary (GU) system
- Panel of genes associated with inherited prostate cancer and an increased lifetime risk of developing prostate cancer or other cancers (15 genes).
- Panel of genes associated with hereditary renal or urinary tract cancers, including cancers of the kidneys, renal pelvis, ureters, bladder and ureter (30 genes).
Soft tissue malignancy (sarcomas)
- Panel of genes associated with hereditary sarcomas, including bone and soft tissue sarcomas (41 genes).
Cancer somatic gene abnormalities
Solid tissue tumors
- Comprehensive panel for solid tumors (67 genes).
Organ specific solid tissue tumor gene panel
- Lung tumor panel (26 genes).
- Brain tumor panel (37 genes).
- Breast tumor panel (24 genes).
- Cervical tumor panel (23 genes).
- Ovarian tumor panel (24 genes).
- Endometrial tumor panel (22 genes).
- Esophagus tumor panel (25 genes).
- Gastric tumor panel (25 genes).
- Colorectal tumor panel (25 genes).
- Liver/biliary tumor panel (25 genes).
- Pancreatic tumor panel (27 genes).
- Head and neck tumor panel (26 genes).
- Melanoma panel (19 genes).
- Thyroid tumor panel (17 genes).
Hematologic tumors
- Comprehensive gene panel for hematologic tumors (76 genes).
- Panels for specific hematologic tumors.
- Acute myeloid leukemia (AML, 29 genes).
- Chronic lymphocytic leukemia (CLL, 11 genes).
- Juvenile myelomonocyte leukemia (JMML, 15 genes).
- Lymphoma (8 genes).
- Myelodysplastic syndrome/chronic myelomonocyte leukemia (MDS/CMML, 31 genes).
- Myeloproliferative neoplasms (MPN, 24 genes).
Fusion gene panels
- Comprehensive fusion gene panel (152 genes).
- Individual fusion gene panels.
- Comprehensive sarcoma fusion panel (27 genes).
- Comprehensive solid tumor fusion gene panel (54 genes).
- Comprehensive hematologic neoplasm fusion gene panel (76 genes).
- Individual hematologic tumor fusion gene panels.
- Acute lymphoblastic leukemia (ALL, 45 genes).
- Myeloproliferative neoplasms (PMN, 39 genes).
- Lymphomas (32 genes).
Cell free tumor DNA (cfDNA) assays
- Pan-cancer cfDNA assay for solid tumors (52 genes).
- Organ specific cfDNA cancer gene panels
- Lung cancer cfDNA assay panel (11 genes).
- Breast cancer cfDNA assay panel (10 genes).
- Colon cancer cfDNA assay panel (14 genes).
- cfDNA assays for hematologic diseases.
- Pan-hematological disease cfDNA assay (60 genes).
- Hematological disease specific cfDNA assays
- AML profile (24 genes); MDS/CMML profile (31 genes).
- Myeloid disorders profile (56 genes).
Tests for cancer immunotherapy
- Tumor mutation burdan (tmb).
- Immunohistochemical stains: pd-l1, pd-1.
Fluorescence in situ hybridization (FISH)
Diagnostic gene testing
A genetic disease or disorder is the result of mutations or alterations in an individual’s DNA. There are more than 10,000 different genetic conditions.
Genetics 101
Cardiovascular diseases
Arrhythmia panels
- Basic arrhythmia panel (47 genes).
- Comprehensive arrhythmia panel (176 genes).
Cardiomyopathy panels
- Basic cardiomyopathy panel (94 genes).
- Comprehensive cardiomyopathy panel (227 genes).
Combined cardiomyopathy and arrhythmia panel
- Basic combined cardiomyopathy and arrhythmia panel (131 genes).
- Comprehensive cardiomyopathy and arrhythmia panel (224 genes).
Combined cardiovascular panels
- Basic combined cardiovascular panel (106 genes).
- Comprehensive combined cardiovascular panel (241 genes).
Panels for individual cardiovascular diseases
- Arrhythmogenic right ventricular cardiomyopathy (ARVC, 14 genes).
- Catecholaminergic polymorphic ventricular tachycardia (CPVT, 8 genes).
- Dilated cardiomyopathy (DCM, 66 genes).
- Familial hypercholesterolemia (FH, 4 genes).
- Hypertrophic cardiomyopathy (HCM).
- Left ventricular non-compaction (LVNC) (8 genes).
- Thoracic aortic aneurysms and dissections (TAAD)/Marfan syndrome and related disorders (24 genes).
- Brugada syndrome (BrS, 14 genes).
- Long QT syndrome (LQTS, 17 genes).
- Short QT syndrome (SQTS, 5 genes).
- Noonan Spectrum and RASopathies panel (19 genes).
- Heritable disorders of connective tissue (HDCT, 49 genes).
- Sudden cardiac arrest panel (13 genes).
Neurological disorders
- Epilepsy panels
- Febrile seizure (13 genes).
- Infantile epilepsy (113 genes).
- Childhood-onset epilepsy panel (82 genes).
- STAT epilepsy panel (26 genes).
- Comprehensive epilepsy panel (149 genes).
- Hearing loss (126 genes).
- Autism panel (116 genes).
- Intellectual disability panel (140 genes).
Reproductive health
Prenatal tests
- Non-invasive prenatal test (NIPT).
- Prenatal significant genetic disorder panel (30 genes/49 disorders).
Carrier screening
- AOCG/AOMG recommended panel (27 genes).
- Expanded carrier screening panel (250 genes).
- Whole exome carrier screening panel (2,100 genes).
Pharmacogenetics & metabolic issues
- Comprehensive pharmacogenetics panel (45 genes).
- Comprehensive panel of inborn errors of metabolism (594 genes).
Whole genome & clinical exome sequencing
Potential utilization:
- PHARMA research.
- Genetic diseases.
- Non-medical health check-up.
- Metagenomics for use of genomic identification of infectious microorganisms.